Endocrine Abstracts

Increased mammary metabolism after child-birth supports the synthesis of milk components and is critical for initiating lactation during postpartum days 1-4. We utilised clinical and cellular approaches to investigate whether growth hormone (GH), which is reported to increase milk yield in breastfeeding women, may play a role in initiating lactation and promoting mammary metabolism. We recruited n=30 pregnant women (age range 24-41 years) following informed consent an...

The onset of lactation during post-partum days 1-4 is hormonally-regulated and critical for successful breastfeeding. Insulin represents a key lactogenic hormone as evidenced by women with type 1 diabetes who have delayed lactation onset. However, the role of insulin in lactation and its influence on mammary cells are unclear. We utilised clinical and cellular approaches to investigate this, and recruited n=12 women following informed consent and measured serum insuli...